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CAS NO.19356-17-3
Factory direct sales high grade top purity Calcifediol 19356-17-3 with fast shipping, accept customization.
Calcifediol, also known as calcidiol or 25-hydroxycholecalciferol, is a vitamin D derivative produced in the liver through the hydroxylation of vitamin D? by the enzyme vitamin D 25-hydroxylase. Calcifediol may have serious side effects. If you experience symptoms such as shortness of breath, swelling, rapid weight gain, or high calcium levels (manifested as confusion, tiredness, nausea, vomiting, loss of appetite, constipation, increased thirst, or urination, and weight loss), it is crucial to contact your doctor promptly. Calcifediol serves to treat hyperparathyroidism in individuals with kidney disease.
Kind Pharma has its own laboratory, which can do analytical testing for API (Active Pharmaceutical Ingredient), pharmaceutical intermediate, pesticide intermediate, additive and other chemical products, so it can make sure Quality Assurance. We are able to analyze the purity, content, gas phase, melting point, specific rotation, UV, weight loss, burning residue and titration of API and Intermediate.
Is calcifediol better than cholecalciferol for vitamin D supplementation?
J. M. Quesada-Gomez & R. Bouillon
Osteoporosis International, 2018
We reviewed all publications dealing with a comparison of oral cholecalciferol with oral calcifediol as to define the relative efficacy of both compounds for improving the vitamin D status. Finally, intermittent intake of calcifediol results in fairly stable serum 25OHD compared with greater fluctuations after intermittent oral cholecalciferol.
Hypovitaminosis D: Is It Time to Consider the Use of Calcifediol?
Roberto Cesareo 1,*,Alberto Falchetti 2,Roberto Attanasio 3,Gaia Tabacco 4,Anda Mihaela Naciu 4 andAndrea Palermo 4
Nutrients 2019, 11(5), 1016;
Calcifediol is more soluble than cholecalciferol in organic solvents, due to its high polarity. Good intestinal absorption and high affinity for the vitamin-D-binding protein positively affect the bioavailability of calcifediol compared with cholecalciferol. The authors highlighted that oral calcifediol seemed to be 4.2–5 times more potent than oral cholecalciferol.