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CAS NO.187393-00-6
Factory Supply High Purity 187393-00-6 with Low Price, Offer Bemotrizinol (Tinosorb S), accept customization.
Bemotrizinol, also known as Tinosorb S, is an oil-soluble organic compound added to sunscreens for UV absorption.
Marketed as Parsol Shield, Tinosorb S, and Escalol S.
Widely used in sunscreens in Australasia and Europe but not in the USA.
Broad-spectrum UV absorber, effectively absorbing both UVA and UVB rays.
Functions as a stabilizer for other filters, particularly enhancing the stability of avobenzone.
Deemed safe by scientific data, but the FDA has not approved its use in the USA.
FDA claims a rigorous testing process for sunscreen ingredients.
Molecular formula: C38H49N3O5
Slightly yellow crystals with a melting point of 83–85°C (Hüglin)
Soluble in oil
Absorption maxima of 343 nm (ε 47000) in ethanol and 341 nm (ε 790) in isopropanol.
Stability is crucial for optimum skin protection against sun rays.
Studies on photolytic exposure, thermal exposure, oxidation, acid hydrolysis, and base hydrolysis were conducted.
Correction to: Molecular modeling as a design tool for sunscreen candidates: a case study of bemotrizinol
João Victor Teixeira Gomes, Anne Cherem Peixoto da Silva, Murilo Lamim Bello, Carlos Rangel Rodrigues & Bianca Aloise Maneira Corrêa Santos
Journal of Molecular Modeling (2019) 25:362
Bemotrizinol is added to the different sunscreen preparations … The stability of Bemotrizinol is very important in different … and base hydrolysis of Bemotrizinol was study with photo diode …
ENHANCING THE SUNSCREEN EFFICACY OF BEMOTRIZINOL MICROPIGMENT BY USING O/W NANOEMULSION TOPICAL PREPARATIONS
DINA M. HASHIM1, NERMIN M. SHETA2, VIVIAN S. ELWAZZAN1, WEDAD SAKRAN3
International Journal of Pharmacy and Pharmaceutical Sciences Print ISSN: 2656-0097 | Online ISSN: 0975-1491
: Bemotrizinol (BEMT) is the most efficient broad-spectrum UV-absorber having a dual mechanism of action in absorbing and reflecting photons. The main objective of this work was to develop successful oil in water (o/w) nanoemulsion for improving the solubility of BEMT and its protective characteristics.