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CAS NO.161596-47-0
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(S)-(+)-Glycidyl Phthalimide is a valuable intermediate in the production of pharmaceuticals, contributing to the synthesis of antibiotic and anticoagulant medications.
(Applications and Significance):
Antibiotic Linezolid:
Used as an intermediate in the synthesis of the antibiotic Linezolid.
Linezolid is an antibiotic effective against various Gram-positive bacteria.
Rivaroxaban:
Serves as a key intermediate in the synthesis of rivaroxaban.
Rivaroxaban is an anticoagulant medication used to prevent and treat blood clots.
(Additional Information):
(S)-(+)-Glycidyl Phthalimide plays a crucial role in the pharmaceutical industry, contributing to the synthesis of important medications.
The compound's stereochemistry is specified as (S)-(+)-, indicating the chirality of the molecule.
(Compound Identification):
CAS Number: A unique identifier for the compound.
Empirical Formula: Represents the relative number of atoms of each element in the compound.
CID: Compound Identifier, a reference number in the PubChem database.
(Disclaimer):
Use of the compound in pharmaceutical synthesis should adhere to applicable laws and regulations.
Information provided here is for informative purposes and does not encourage or endorse unauthorized use.
Anionic ring-opening polymerization of N-glycidylphthalimide: Combination of phosphazene base and activated monomer mechanism
Somasoudrame Rassou, Nicolas Illy, Ozgul Tezgel, Philippe Guégan
Journal of Polymer Science Part A: Polymer Chemistry, Volume56, Issue10 May 15, 2018 Pages 1091-1099
Anionic ring-opening polymerization of glycidyl phthalimide, initiated with alcohol–phosphazene base systems and based on monomer activation with a Lewis acid (iBu3Al), has been studied. No propagation occurred for initiator: iBu3Al ratios less or equal to 1:3.
Functional PEG-based polymers with reactive groups via anionic ROP of tailor-made epoxides
Christine Mangold,ab Frederik Wurmac and Holger Frey*a
Polymer Chemistry, Issue 7, 2012
In this review article functional epoxide monomers that are suitable for controlled ring-opening polymerization (ROP) are discussed. Functional epoxides possess reactive groups, which either are directly accessible or carry suitable protective groups that can be removed in a facile one-step reaction after polymerization.