Tianjin Kind Pharma Co., Ltd.
Assessed Supplier Enterprise Certification
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Assessed Supplier Enterprise Certification
Business Type:Lab/Research institutions
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Lab/Research institutions
Tel: +86-15510908448
Mobile: +86-15510908448
Tel: +86-15510908448
Fax: +86-15510908448
URL: http://www.kindpharma.biz
Province/state: Tianjin
City: Tianjin
Street: No.22 Quanwang Road, Wuqing Development Zone, Tianjin, China
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CAS NO.133242-30-5
Top(1-100)Kilogram
Factory direct sales, accept customization.
Landiolol was launched as iv infusion for the treatment of tachyarrhythmia during surgery. This structurally related derivative of esmolol can be synthesized in 3 linear steps from 3-(4-hydroxyphenyl)propionic acid by successive esterification followed by alkylation of the phenol function with (2S)-glycidyltosylate and opening of the resulting epoxide by the appropriate amine. Landiolol is an ultra short acting PI-adrenergic blocker more cardioselective (βI/β2 = 255) than esmolol (βi/β2 = 32). It showed 6-8 times greater efficiency compared to esmolol in reducing isoproterenol-induced increase in heart rate and ventricular contraction in anesthetized dogs. In clinical trials, landiolol was effective against a variety of arrhythmias with efficacy seen in patients with atrial fibrillation, proxysmal supraventricular tachycardia, ventricular tachycardia and premature complexes. Landiolol produced a doserelated pharmacokinetic behavior, has a rapid onset of action (10 min.) and is rapidly hydrolyzed to inactive acidic metabolites by esterases after iv administration. This results in an ultra-short half-life (approx. 3 min.) and p-blocade, allowing rapid termination of the drug effect by termination of infusion if side effects occur. Hypertension was the most frequent adverse event and resolved in less than 30 min. after drug withdrawal.
Kind Pharma has its own laboratory, we can do analytical testing for API (Active Pharmaceutical Ingredient), pharmaceutical intermediate, pesticide intermediate, additive and other chemical products, so it can make sure Quality Assurance.
Professional Staff
Our laboratory department is run by our highly skilled QC team consists of analytical chemists and laboratory technicians. We can ensure that our company can provide you professional and efficient service.
Professional Equipments and Instruments
Our advanced laboratory is furnished with all the necessary equipments and instruments to process the analysis of substances. Including HPLC,GC,Moisture Analyzer, Melting Point Meter, Polarimeter, UV Spectrophotometer, Drying Oven, Muffle Furnace, etc.
We are able to analyze the purity, content, gas phase, melting point, specific rotation, UV, weight loss, burning residue and titration of API and Intermediate.
Quality Police
We have already introduced advanced analytical instruments to evaluate the quality of API/Intermediate, set API/Intermediate specifications and testing methods. Our analytical laboratory is constantly being updated to meet pharmaceutical industry standards and customer expectations. we are determined to continuously contribute to the growth of the pharmaceutical industry and support people for their healthier lives.
Landiolol was launched as iv infusion for the treatment of tachyarrhythmia during surgery. This structurally related derivative of esmolol can be synthesized in 3 linear steps from 3-(4-hydroxyphenyl)propionic acid by successive esterification followed by alkylation of the phenol function with (2S)-glycidyltosylate and opening of the resulting epoxide by the appropriate amine. Landiolol is an ultra short acting PI-adrenergic blocker more cardioselective (βI/β2 = 255) than esmolol (βi/β2 = 32). It showed 6-8 times greater efficiency compared to esmolol in reducing isoproterenol-induced increase in heart rate and ventricular contraction in anesthetized dogs. In clinical trials, landiolol was effective against a variety of arrhythmias with efficacy seen in patients with atrial fibrillation, proxysmal supraventricular tachycardia, ventricular tachycardia and premature complexes. Landiolol produced a doserelated pharmacokinetic behavior, has a rapid onset of action (10 min.) and is rapidly hydrolyzed to inactive acidic metabolites by esterases after iv administration. This results in an ultra-short half-life (approx. 3 min.) and p-blocade, allowing rapid termination of the drug effect by termination of infusion if side effects occur. Hypertension was the most frequent adverse event and resolved in less than 30 min. after drug withdrawal.
Tianjin Kind Pharma Co., Ltd., founded in 2013, which is located in Wuqing Development Zone, Tianjin, China, and it is convenient for transportation. We are a professional manufacturer and exporter specializing in API (Active Pharmaceutical Ingredient), Pharmaceutical Intermediate, Pesticide Intermediate, Additive and other chemical products. Our company insists on quality-driven development, continuously improving the level of enterprise management and strengthening the awareness of quality control and risk management, we have played an important role in promoting the innovation and development of Chinese pharmaceutical industry.
Our company has first-class technical personnel, senior R&D team, advanced production equipment, efficient, compliant, flexible production capacity and quality management capability, sound Q.A. System and testing method, perfect marketing network, excellent logistics distribution, and quick response after-sales service. Our products are produced in strict accordance with GMP requirements, in line with international standards. In addition, we can also provide Contract Development Manufacture Organization (CDMO) services according to customer’s requirement. At present, our company has established long-term and stable strategic partnership with many internationally renowned pharmaceutical companies, and we have been recognized by many domestic and international drug regulatory agencies. Our products have received unanimous praise from customers in the Europe, North America, South America, South Korea, New Zealand, and Southeast Asia.
We adhere to the principle of "Technological Innovation, Service First" and customer-oriented, providing customers with one-stop and personalized solutions and professional and reliable services. Warmly welcome friends to visit and cooperate from all over the world.
Vision: To be the world's leading Contract Development Manufacture Organization (CDMO) enterprise and international trade platform for the pharmaceutical industry.
Mission: To provide customers with the best customized services and one-stop solutions, enhance customer satisfaction with our company, and promote innovation and development in the global pharmaceutical industry.